Prediction and biochemical analysis of putative cleavage sites of the 3C-like protease of Middle East respiratory syndrome coronavirus

Coronavirus 3C-like protease (3CLpro) is responsible for the cleavage of coronaviral polyprotein 1a/1ab (pp1a/1ab) to produce the mature non-structural proteins (nsps) of nsp4–16. The nsp5 of the newly emerging Middle East respiratory syndrome coronavirus (MERS-CoV) was identified as 3CLpro and its...

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Publicado no:Virus Res
Main Authors: Wu, Andong, Wang, Yi, Zeng, Cong, Huang, Xingyu, Xu, Shan, Su, Ceyang, Wang, Min, Chen, Yu, Guo, Deyin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114542/
https://ncbi.nlm.nih.gov/pubmed/26036787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2015.05.018
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