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Characterization of the spike protein of human coronavirus NL63 in receptor binding and pseudotype virus entry

The spike (S) protein of human coronavirus NL63 (HCoV-NL63) mediates both cell attachment by binding to its receptor hACE2 and membrane fusion during virus entry. We have previously identified the receptor-binding domain (RBD) and residues important for RBD–hACE2 association. Here, we further charac...

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Dettagli Bibliografici
Pubblicato in:Virus Res
Autori principali: Lin, Han-Xin, Feng, Yan, Tu, Xinming, Zhao, Xuesen, Hsieh, Chih-Heng, Griffin, Lauren, Junop, Murray, Zhang, Chengsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114368/
https://ncbi.nlm.nih.gov/pubmed/21798295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2011.06.029
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