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In silico and in vitro analysis of small molecules and natural compounds targeting the 3CL protease of feline infectious peritonitis virus

The computational search of chemical libraries has been used as a powerful tool for the rapid discovery of candidate compounds. To find small molecules with anti-feline infectious peritonitis virus (FIPV) properties, we utilized a virtual screening technique to identify the active site on the viral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antiviral Res
Hauptverfasser: Theerawatanasirikul, Sirin, Kuo, Chih Jung, Phetcharat, Nanthawan, Lekcharoensuk, Porntippa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114316/
https://ncbi.nlm.nih.gov/pubmed/31863793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104697
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