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Structure-based antigen design: a strategy for next generation vaccines

Vaccine design is progressing from empiricism towards the increasingly rational presentation of the targets of protective immunity. Nevertheless, most current vaccine antigens are essentially the native macromolecules of pathogens. These molecules are adapted to evade, not induce, immunity. High res...

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Detalhes bibliográficos
Publicado no:Trends Biotechnol
Main Authors: Dormitzer, Philip R., Ulmer, Jeffrey B., Rappuoli, Rino
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114313/
https://ncbi.nlm.nih.gov/pubmed/18977045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2008.08.002
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