Inhibition of human coronavirus 229E infection in human epithelial lung cells (L132) by chloroquine: Involvement of p38 MAPK and ERK

The antiviral effects of chloroquine (CQ) on human coronavirus 229E (HCoV-229E) infection of human fetal lung cell line, L132 are reported. CQ significantly decreased the viral replication at concentrations lower than in clinical usage. We demonstrated that CQ affects the activation of p38 mitogen-a...

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I publikationen:Antiviral Res
Huvudupphovsmän: Kono, Masakazu, Tatsumi, Koichiro, Imai, Alberto M., Saito, Kengo, Kuriyama, Takayuki, Shirasawa, Hiroshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier B.V. 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114149/
https://ncbi.nlm.nih.gov/pubmed/18055026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2007.10.011
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