Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus

The activity of inosine-5′-monophosphate dehydrogenase (IMPDH) inhibitors, mizoribine and ribavirin, against severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) was determined by plaque reduction and yield reduction assays. Mizoribine and ribavirin selectively inhibited replic...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Saijo, Masayuki, Morikawa, Shigeru, Fukushi, Shuetsu, Mizutani, Tetsuya, Hasegawa, Hideki, Nagata, Noriyo, Iwata, Naoko, Kurane, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114120/
https://ncbi.nlm.nih.gov/pubmed/15911031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2005.01.003
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