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A potential role for integrins in host cell entry by SARS-CoV-2

• Integrin may act as an alternative receptor for SARS-CoV-2 and could be implicated in its transmission and pathology. • The spike protein of SARS-CoV-2 acquired a RGD motif known to bind integrins. This motif is absent from other coronaviruses. • The integrin-binding motif is present at the surfac...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Sigrist, Christian JA, Bridge, Alan, Le Mercier, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. Published by Elsevier B.V. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114098/
https://ncbi.nlm.nih.gov/pubmed/32130973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104759
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