Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice

Middle East respiratory syndrome coronavirus (MERS-CoV) has continued spreading since its emergence in 2012 with a mortality rate of 35.6%, and is a potential pandemic threat. Prophylactics and therapies are urgently needed to address this public health problem. We report here the efficacy of a vacc...

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Vydáno v:Antiviral Res
Hlavní autoři: Wang, Chong, Zheng, Xuexing, Gai, Weiwei, Wong, Gary, Wang, Hualei, Jin, Hongli, Feng, Na, Zhao, Yongkun, Zhang, Weijiao, Li, Nan, Zhao, Guoxing, Li, Junfu, Yan, Jinghua, Gao, Yuwei, Hu, Guixue, Yang, Songtao, Xia, Xianzhu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113847/
https://ncbi.nlm.nih.gov/pubmed/28040513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.12.019
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