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Construction of an infectious cDNA clone of Enterovirus 71: Insights into the factors ensuring experimental success

Enterovirus 71 (EV 71) is a causative agent of mild Hand Foot and Mouth Disease but is capable of causing severe complications in the CNS in young children. Reverse genetics technology is currently widely used to study the pathogenesis of the virus. The aim of this work was to determine and evaluate...

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Detalhes bibliográficos
Publicado no:J Virol Methods
Main Authors: Lazouskaya, Natallia V., Palombo, Enzo A., Poh, Chit-Laa, Barton, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. Published by Elsevier B.V. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113652/
https://ncbi.nlm.nih.gov/pubmed/24361875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2013.12.005
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