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Baculovirus expression of HCoV-OC43 nucleocapsid protein and development of a Western blot assay for detection of human antibodies against HCoV-OC43

The nucleocapsid (N) gene of human coronavirus strain OC43 (HCoV-OC43) was amplified by reverse transcriptase-polymerase chain reaction, and cloned in pENTR™/D-TOPO(®) plasmid. This plasmid containing the N gene was recombined with in a BaculoDirect™ baculovirus DNA designed in order to express N pr...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol Methods
Hauptverfasser: Mourez, Thomas, Vabret, Astrid, Han, Yang, Dina, Julia, Legrand, Loïc, Corbet, Sandrine, Freymuth, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112889/
https://ncbi.nlm.nih.gov/pubmed/17079026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2006.09.024
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