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Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide

Low oral bioavailability of peptide drugs has limited their application to parenteral administration, which suffers from poor patient compliance. Here, we show that molecular targeting of the FATP4 transporter is an effective approach to specifically transport long-chain fatty acid (LCFA)–conjugated...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Hu, Zhenhua, Nizzero, Sara, Goel, Shreya, Hinkle, Louis E., Wu, Xiaoyan, Li, Chao, Ferrari, Mauro, Shen, Haifa
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112756/
https://ncbi.nlm.nih.gov/pubmed/32270048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba0145
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