The antiviral activity of poly-γ-glutamic acid, a polypeptide secreted by Bacillus sp., through induction of CD14-dependent type I interferon responses

Poly-γ-glutamic acid (γ-PGA) is an anionic polypeptide secreted by Bacillus sp. that has been shown to activate immune cells through interactions with toll-like receptor 4 (TLR4). However, its ability to induce the type I interferon (IFN) response has not yet been characterized. Here, we demonstrate...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Lee, Wooseong, Lee, Seung-Hoon, Ahn, Dae-Gyun, Cho, Hee, Sung, Moon-Hee, Han, Seung Hyun, Oh, Jong-Won
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112489/
https://ncbi.nlm.nih.gov/pubmed/24016850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.08.067
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