Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS

BACKGROUND: The outbreak of severe acute respiratory syndrome (SARS) in 2002 was caused by a previously unknown coronavirus—SARS coronavirus (SARS-CoV). We have developed an experimental SARS vaccine for direct immunisation of the respiratory tract, the major site of SARS-coronavirus transmission an...

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Publicat a:Lancet
Autors principals: Bukreyev, Alexander, Lamirande, Elaine W, Buchholz, Ursula J, Vogel, Leatrice N, Elkins, William R, Claire, Marisa St, Murphy, Brian R, Subbarao, Kanta, Collins, Peter L
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112367/
https://ncbi.nlm.nih.gov/pubmed/15220033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(04)16501-X
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