HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened

Loss of pancreatic β-cell mass and function as a result of sustained ER stress is a core step in the pathogenesis of diabetes mellitus type 2. The complex control of β-cells and insulin production involves hedgehog (Hh) signaling pathways as well as cholesterol-mediated effects. In fact, data from s...

Full description

Saved in:
Bibliographic Details
Published in:J Lipid Res
Main Authors: Yalcinkaya, Mustafa, Kerksiek, Anja, Gebert, Katrin, Annema, Wijtske, Sibler, Rahel, Radosavljevic, Silvija, Lütjohann, Dieter, Rohrer, Lucia, von Eckardstein, Arnold
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2020
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112150/
https://ncbi.nlm.nih.gov/pubmed/31907205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000509
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items