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Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents

A series of novel acyl-hydrazone (4a-d) and spirothiazolidinone (5a-d, 6a-d) derivatives of imidazo[2,1-b]thiazole were synthesized and evaluated for their antiviral and antimycobacterial activity. The antituberculosis activity was evaluated by using the Microplate Alamar Blue Assay and the antivira...

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Vydáno v:Bioorg Chem
Hlavní autoři: Gürsoy, Elif, Dincel, Efe Doğukan, Naesens, Lieve, Ulusoy Güzeldemirci, Nuray
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112121/
https://ncbi.nlm.nih.gov/pubmed/31862455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2019.103496
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