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A highly facile approach to the synthesis of novel 2-(3-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-N-phenylacetamides

A series of heterocyclic compounds were designed as potential nonnucleoside HIV reverse transcriptase inhibitors. Although the compounds ultimately proved inactive against HIV, during the course of the synthesis, a new and highly facile method to realize N-phenylacetamides was developed. Notably, th...

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron Lett
Hauptverfasser: Novikov, Mikhail S., Babkov, Denis A., Paramonova, Maria P., Chizhov, Alexander O., Khandazhinskaya, Anastasia L., Seley-Radtke, Katherine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111777/
https://ncbi.nlm.nih.gov/pubmed/32287444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.11.090
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