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Deoxygenation of 5-O-benzoyl-1,2-isopropylidene-3-O-imidazolylthiocarbonyl-α-d-xylofuranose using dimethyl phosphite: an efficient alternate method towards a 3′-deoxynucleoside glycosyl donor

An efficient radical deoxygenation reaction of thiocarbonylimidazolyl activated glycoside analogue using dimethyl phosphite as hydrogen source and radical chain carrier was performed as a key step in a multi step synthesis towards a common 3-deoxy glycosyl donor for 3′-deoxynucleosides. This method...

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Veröffentlicht in:Tetrahedron Lett
Hauptverfasser: Zlatev, Ivan, Vasseur, Jean-Jacques, Morvan, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111737/
https://ncbi.nlm.nih.gov/pubmed/32287438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.03.079
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