Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO

Porcine deltacoronavirus (PDCoV) causes acute enteric disease and mortality in seronegative neonatal piglets. Previously we have demonstrated that PDCoV infection suppresses the production of interferon-beta (IFN-β), while the detailed mechanisms are poorly understood. Here, we demonstrate that nons...

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Bibliographic Details
Published in:Virology
Main Authors: Zhu, Xinyu, Fang, Liurong, Wang, Dang, Yang, Yuting, Chen, Jiyao, Ye, Xu, Foda, Mohamed Frahat, Xiao, Shaobo
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111669/
https://ncbi.nlm.nih.gov/pubmed/27984784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.12.005
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