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Genomic loci susceptible to systematic sequencing bias in clinical whole genomes

Accurate massively parallel sequencing (MPS) of genetic variants is key to many areas of science and medicine, such as cataloging population genetic variation and diagnosing genetic diseases. Certain genomic positions can be prone to higher rates of systematic sequencing and alignment bias that limi...

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Podrobná bibliografie
Vydáno v:Genome Res
Hlavní autoři: Freeman, Timothy M., Wang, Dennis, Harris, Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111519/
https://ncbi.nlm.nih.gov/pubmed/32156711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.255349.119
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