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Protection against infectious bronchitis virus by spike ectodomain subunit vaccine

The avian coronavirus infectious bronchitis virus (IBV) S1 subunit of the spike (S) glycoprotein mediates viral attachment to host cells and the S2 subunit is responsible for membrane fusion. Using IBV Arkansas-type (Ark) S protein histochemistry, we show that extension of S1 with the S2 ectodomain...

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Publicado en:Vaccine
Main Authors: Eldemery, Fatma, Joiner, Kellye S., Toro, Haroldo, van Santen, Vicky L.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Ltd. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111290/
https://ncbi.nlm.nih.gov/pubmed/28899630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.09.013
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