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QSAR modelling and molecular docking studies for anti-cancer compounds against melanoma cell line SK-MEL-2

A dataset of seventy-two (72) cytotoxic compounds of the National Cancer Institute (NCI) was studied by QSAR and docking approaches to gain deeper insights into ligands selectivity on SK-MEL-2 cell line. The QSAR model was built using fifty (50) molecules and the best-generated model based on multip...

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Bibliografiske detaljer
Udgivet i:Heliyon
Main Authors: Umar, Abdullahi Bello, Uzairu, Adamu, Shallangwa, Gideon Adamu, Uba, Sani
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110328/
https://ncbi.nlm.nih.gov/pubmed/32258485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e03640
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