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A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing

Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral quasispecies by this methodology. In this work we present a suitable and affor...

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Publicat a:Brief Bioinform
Autors principals: Cacciabue, Marco, Currá, Anabella, Carrillo, Elisa, König, Guido, Gismondi, María Inés
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110011/
https://ncbi.nlm.nih.gov/pubmed/31697321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbz086
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