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5-Carboxylcytosine and Cytosine Protonation Distinctly Alter the Stability and Dehybridization Dynamics of the DNA Duplex

Applications associated with nucleobase protonation events are grounded in their fundamental impact on DNA thermodynamics, structure, and hybridization dynamics. Of the canonical nucleobases, N3 protonation of cytosine (C) is the most widely utilized in both biology and nanotechnology. Naturally occ...

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Publicat a:J Phys Chem B
Autors principals: Ashwood, Brennan, Sanstead, Paul J., Dai, Qing, He, Chuan, Tokmakoff, Andrei
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109620/
https://ncbi.nlm.nih.gov/pubmed/31873021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b11510
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