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NKG2D Ligand Shedding in Response to Stress: Role of ADAM10

NKG2D is an activating receptor expressed by NK cells and some subsets of T cells and represents a major recognition receptor for detection and elimination of cancer cells. The ligands of NKG2D are stress-induced self-proteins that can be secreted as soluble molecules by protease-mediated cleavage....

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Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Zingoni, Alessandra, Vulpis, Elisabetta, Loconte, Luisa, Santoni, Angela
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109295/
https://ncbi.nlm.nih.gov/pubmed/32269567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00447
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