TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice

Non-alcoholic fatty liver disease (NAFLD) shows an increasing prevalence and is associated with the development of liver fibrosis and cirrhosis as the major risk factors of liver-related mortality in this disease. The therapeutic possibilities are limited and restricted to life style intervention, s...

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Pubblicato in:Cell Death Dis
Autori principali: Wandrer, Franziska, Liebig, Stephanie, Marhenke, Silke, Vogel, Arndt, John, Katharina, Manns, Michael P., Teufel, Andreas, Itzel, Timo, Longerich, Thomas, Maier, Olaf, Fischer, Roman, Kontermann, Roland E., Pfizenmaier, Klaus, Schulze-Osthoff, Klaus, Bantel, Heike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109108/
https://ncbi.nlm.nih.gov/pubmed/32235829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2411-6
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