Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation

Visceral adipose tissue plays a critical role in numerous diseases. Although imaging studies often show adipose involvement in abdominal diseases, their outcomes may vary from being a mild self-limited illness to one with systemic inflammation and organ failure. We therefore compared the pattern of...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: de Oliveira, Cristiane, Khatua, Biswajit, Noel, Pawan, Kostenko, Sergiy, Bag, Arup, Balakrishnan, Bijinu, Patel, Krutika S., Guerra, Andre A., Martinez, Melissa N., Trivedi, Shubham, McCullough, Ann, Lam-Himlin, Dora M., Navina, Sarah, Faigel, Douglas O., Fukami, Norio, Pannala, Rahul, Phillips, Anna Evans, Papachristou, Georgios I., Kershaw, Erin E., Lowe, Mark E., Singh, Vijay P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108918/
https://ncbi.nlm.nih.gov/pubmed/31917686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132767
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