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Intrinsic antiviral immunity drives neurodegeneration in Alzheimer disease

β-Amyloid aggregates found in brain plaques are viewed as triggers of cytotoxicity and neuroinflammation in Alzheimer disease (AD). However, the main β-amyloid (Aβ) species and what imbues the aggregates with such toxic potential are still not yet understood. In this issue of the JCI, Roy et al. sho...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pluchino, Stefano, Willis, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108882/
https://ncbi.nlm.nih.gov/pubmed/32149728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135906
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