Emergence and Selection of a Highly Pathogenic Avian Influenza H7N3 Virus

Low-pathogenicity avian influenza (LPAI) viruses of subtypes H5 and H7 have the ability to spontaneously mutate to highly pathogenic (HPAI) virus variants, causing high mortality in poultry. The highly pathogenic phenotype is caused by mutation of the hemagglutinin (HA) cleavage site, but additional...

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Vydáno v:J Virol
Hlavní autoři: Beerens, Nancy, Heutink, Rene, Harders, Frank, Bossers, Alex, Koch, Guus, Peeters, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108855/
https://ncbi.nlm.nih.gov/pubmed/31969434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01818-19
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