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Basic Amino Acid Substitution at Residue 367 of the Envelope Protein of Tembusu Virus Plays a Critical Role in Pathogenesis

Tembusu virus (TMUV) is a flavivirus responsible for panzootic outbreaks of severe egg-drop and fatal encephalitis of domestic waterfowl in China. Although TMUV can be attenuated by in vitro passaging, experimental evidence supporting the role of specific genetic changes in virulence attenuation is...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sun, Mengxu, Zhang, Lijiao, Cao, Yanxin, Wang, Jun, Yu, Ziding, Sun, Xue, Liu, Fengli, Li, Zhuolin, Liu, Pinghuang, Su, Jingliang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108846/
https://ncbi.nlm.nih.gov/pubmed/32024774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02011-19
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