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A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters

Synthetic sex distorters have recently been developed in the malaria mosquito, relying on endonucleases that target the X-chromosome during spermatogenesis. Although inspired by naturally-occurring traits, it has remained unclear how they function and, given their potential for genetic control, how...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Fasulo, Barbara, Meccariello, Angela, Morgan, Maya, Borufka, Carl, Papathanos, Philippos Aris, Windbichler, Nikolai
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108745/
https://ncbi.nlm.nih.gov/pubmed/32168334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008647
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