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Decreasing fluconazole susceptibility of clinical South African Cryptococcus neoformans isolates over a decade

BACKGROUND: Fluconazole is used in combination with amphotericin B for induction treatment of cryptococcal meningitis and as monotherapy for consolidation and maintenance treatment. More than 90% of isolates from first episodes of cryptococcal disease had a fluconazole minimum inhibitory concentrati...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Naicker, Serisha D., Mpembe, Ruth S., Maphanga, Tsidiso G., Zulu, Thokozile G., Desanto, Daniel, Wadula, Jeannette, Mvelase, Nomonde, Maluleka, Caroline, Reddy, Kessendri, Dawood, Halima, Maloba, Motlatji, Govender, Nelesh P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108701/
https://ncbi.nlm.nih.gov/pubmed/32231354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008137
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