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Bioproduction of ribavirin by green microbial biotransformation

Ribavirin is an antiviral compound widely used in Hepatitis C Virus therapy. Biotransformation of this nucleoside analogue using Escherichia coli ATCC 12407 as biocatalyst is herein reported. Reaction parameters such as microorganism amounts, substrate ratio and temperature were optimized reaching c...

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Bibliografiske detaljer
Udgivet i:Process Biochem
Main Authors: Rivero, Cintia W., De Benedetti, Eliana C., Lozano, Mario E., Trelles, Jorge A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108421/
https://ncbi.nlm.nih.gov/pubmed/32288593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.procbio.2015.03.015
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