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Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome

Type I interferon (IFN) response initially limits HIV-1 spread and may delay disease progression by stimulating several immune system components. Nonetheless, persistent exposure to type I IFN in the chronic phase of HIV-1 infection is associated with desensitization and/or detrimental immune activa...

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Detalhes bibliográficos
Publicado no:Cytokine Growth Factor Rev
Main Authors: Scagnolari, Carolina, Antonelli, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108411/
https://ncbi.nlm.nih.gov/pubmed/29576284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2018.03.003
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