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Large-scale integrated super-computing platform for next generation virtual drug discovery

Traditional drug discovery starts by experimentally screening chemical libraries to find hit compounds that bind to protein targets, modulating their activity. Subsequent rounds of iterative chemical derivitization and rescreening are conducted to enhance the potency, selectivity, and pharmacologica...

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Bibliografiska uppgifter
I publikationen:Curr Opin Chem Biol
Huvudupphovsmän: Mitchell, Wayne, Matsumoto, Shunji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Ltd. 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108376/
https://ncbi.nlm.nih.gov/pubmed/21723773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2011.06.005
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