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A pH-correctable, DNA-based fluorescent reporter for organellar Calcium
It is extremely challenging to quantitate lumenal Ca(2+) in acidic Ca(2+) stores of the cell because all Ca(2+) indicators are pH sensitive, and Ca(2+) transport coupled to pH in acidic organelles. We have developed a fluorescent DNA-based reporter, CalipHluor, that is targetable to specific organel...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7107693/ https://ncbi.nlm.nih.gov/pubmed/30532082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0232-7 |
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