Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform

For antiviral signaling mediated by retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs), the recruitment of cytosolic RLRs and downstream molecules (such as TBK1 and IKKε) to mitochondrial platform is a central event that facilitates the establishment of host antiviral state. Here, we prese...

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Udgivet i:J Mol Cell Biol
Main Authors: Ning, Yun-Jia, Wang, Manli, Deng, Maping, Shen, Shu, Liu, Wei, Cao, Wu-Chun, Deng, Fei, Wang, Yan-Yi, Hu, Zhihong, Wang, Hualin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107466/
https://ncbi.nlm.nih.gov/pubmed/24706939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mju015
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