Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

Middle East respiratory syndrome (MERS) is associated with a mortality rate of >35%. We previously showed that MERS coronavirus (MERS-CoV) could infect human macrophages and dendritic cells and induce cytokine dysregulation. Here, we further investigated the interplay between human primary T cell...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Chu, Hin, Zhou, Jie, Wong, Bosco Ho-Yin, Li, Cun, Chan, Jasper Fuk-Woo, Cheng, Zhong-Shan, Yang, Dong, Wang, Dong, Lee, Andrew Chak-Yiu, Li, Chuangen, Yeung, Man-Lung, Cai, Jian-Piao, Chan, Ivy Hau-Yee, Ho, Wai-Kuen, To, Kelvin Kai-Wang, Zheng, Bo-Jian, Yao, Yanfeng, Qin, Chuan, Yuen, Kwok-Yung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107330/
https://ncbi.nlm.nih.gov/pubmed/26203058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv380
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