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No Benefit of Concomitant 5-Aminosalicylates in Patients with Ulcerative Colitis Escalated to Biologic Therapy: Pooled Analysis of Individual Participant Data from Clinical Trials

BACKGROUND AND AIMS: 5-aminosalicylates (5-ASA) are frequently continued in patients with moderate-severe ulcerative colitis (UC), even after escalation to biologic agents, without evaluation of the benefit of this approach. We conducted an individual participant data (IPD) pooled analysis of trials...

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Bibliografiske detaljer
Udgivet i:Am J Gastroenterol
Main Authors: Singh, Siddharth, Proudfoot, James A., Dulai, Parambir S., Jairath, Vipul, Fumery, Mathurin, Xu, Ronghui, Feagan, Brian G., Sandborn, William J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107271/
https://ncbi.nlm.nih.gov/pubmed/29925913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41395-018-0144-2
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