HJC0152 suppresses human non–small‐cell lung cancer by inhibiting STAT3 and modulating metabolism

OBJECTIVES: Signal transducer and activator of transcription 3 (STAT3) is constitutively activated and overexpressed in many cancers, including non–small‐cell lung cancer (NSCLC). We recently developed HJC0152 as an orally active STAT3 inhibitor. This study focused on investigating HJC0152's ef...

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Vydáno v:Cell Prolif
Hlavní autoři: Lu, Lu, Li, Hang, Wu, Xin, Rao, Jun, Zhou, Jia, Fan, Saijun, Shen, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106968/
https://ncbi.nlm.nih.gov/pubmed/32022328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12777
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