Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells

BACKGROUND: The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for building drug carriers. Genetically engineered silks offer the possibility of...

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Kucharczyk, Kamil, Florczak, Anna, Deptuch, Tomasz, Penderecka, Karolina, Jastrzebska, Katarzyna, Mackiewicz, Andrzej, Dams-Kozlowska, Hanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106823/
https://ncbi.nlm.nih.gov/pubmed/32228620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00609-2
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