Exosomal KRAS mutation promotes the formation of tumor-associated neutrophil extracellular traps and causes deterioration of colorectal cancer by inducing IL-8 expression

BACKGROUND: Colorectal cancer (CRC) remains one of the leading causes of cancer-related death. The current study aimed to elucidate the mechanism by which exosomes carrying KRAS mutant contribute to neutrophil recruitment as well as the formation of the neutrophil extracellular trap (NET) in CRC. ME...

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Detalles Bibliográficos
Publicado en:Cell Commun Signal
Main Authors: Shang, Anquan, Gu, Chenzheng, Zhou, Chen, Yang, Yibao, Chen, Chen, Zeng, Bingjie, Wu, Junlu, Lu, Wenying, Wang, Weiwei, Sun, Zujun, Li, Dong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106821/
https://ncbi.nlm.nih.gov/pubmed/32228650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-0517-1
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