Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

BACKGROUND: During the erythrocytic cycle, Plasmodium falciparum malaria parasites express P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) that anchor the infected erythrocytes (IE) to the vascular lining of the host. The CIDRα1 domain of PfEMP1 is responsible for binding host endothelial prot...

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Enregistré dans:
Détails bibliographiques
Publié dans:Malar J
Auteurs principaux: Harmsen, Charlotte, Turner, Louise, Thrane, Susan, Sander, Adam F., Theander, Thor G., Lavstsen, Thomas
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106694/
https://ncbi.nlm.nih.gov/pubmed/32228596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03201-z
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