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Exogenous supply of Hsp47 triggers fibrillar collagen deposition in skin cell cultures in vitro

BACKGROUND: Collagen is a structural protein that provides mechanical stability and defined architectures to skin. In collagen-based skin disorders this stability is lost, either due to mutations in collagens or in the chaperones involved in collagen assembly. This leads to chronic wounds, skin frag...

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Publicat a:BMC Mol Cell Biol
Autors principals: Khan, Essak S., Sankaran, Shrikrishnan, Llontop, Lorena, del Campo, Aránzazu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106624/
https://ncbi.nlm.nih.gov/pubmed/32228452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00267-0
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