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Structural analysis of inhibition mechanisms of Aurintricarboxylic Acid on SARS-CoV polymerase and other proteins

We recently published experimental results that indicated Aurintricarboxylic Acid (ATA) could selectively inhibit SARS-CoV replication inside host cells by greater than 1000 times. This inhibition suggested that ATA could be developed as potent anti-viral drug. Here, to extend our experimental obser...

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Publicado en:Comput Biol Chem
Autores principales: Yap, YeeLeng, Zhang, XueWu, Andonov, Anton, He, RunTao
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Ltd. 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106521/
https://ncbi.nlm.nih.gov/pubmed/15979041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2005.04.006
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