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Pathophysiological Role of Transient Receptor Potential Mucolipin Channel 1 in Calcium-Mediated Stress-Induced Neurodegenerative Diseases
Mucolipins (TRPML) are endosome/lysosome Ca(2+) permeable channels belonging to the family of transient receptor potential channels. In mammals, there are three TRPML proteins, TRPML1, 2, and 3, encoded by MCOLN1-3 genes. Among these channels, TRPML1 is a reactive oxygen species sensor localized on...
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| Publicat a: | Front Physiol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7105868/ https://ncbi.nlm.nih.gov/pubmed/32265740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00251 |
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