The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking

Nicotinic acetylcholine receptors (AChRs) are pentameric channels that mediate fast transmission at the neuromuscular junction (NMJ) and defects in receptor expression underlie neuromuscular disorders such as myasthenia gravis and congenital myasthenic syndrome (CMS). Nicotinic receptor expression a...

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Foilsithe in:Front Mol Neurosci
Main Authors: Rudell, Jolene Chang, Borges, Lucia Soares, Yarov-Yarovoy, Vladimir, Ferns, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105636/
https://ncbi.nlm.nih.gov/pubmed/32265653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00048
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