The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and loss-of-function assays, we show that in rat hippocampal neurons the MPS is an actomyosin network that controls axonal expansion and contraction. Using s...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Costa, Ana Rita, Sousa, Sara C, Pinto-Costa, Rita, Mateus, José C, Lopes, Cátia DF, Costa, Ana Catarina, Rosa, David, Machado, Diana, Pajuelo, Luis, Wang, Xuewei, Zhou, Feng-quan, Pereira, António J, Sampaio, Paula, Rubinstein, Boris Y, Mendes Pinto, Inês, Lampe, Marko, Aguiar, Paulo, Sousa, Monica M
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105375/
https://ncbi.nlm.nih.gov/pubmed/32195665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55471
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