GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement

CONTEXT: GDF15 is a stress-induced hormone acting in the hindbrain that activates neural circuitry involved in establishing aversive responses and reducing food intake and body weight in animal models. Anorexia, weight loss, nausea and vomiting are common manifestations of glucocorticoid deficiency,...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Endocrinol Metab
Auteurs principaux: Melvin, Audrey, Chantzichristos, Dimitrios, Kyle, Catriona J, Mackenzie, Scott D, Walker, Brian R, Johannsson, Gudmundur, Stimson, Roland H, O’Rahilly, Stephen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Clinical Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105349/
https://ncbi.nlm.nih.gov/pubmed/31853550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz277
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