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Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage
Fanconi-associated nuclease 1 (FAN1) removes interstrand DNA crosslinks (ICLs) through its DNA flap endonuclease and exonuclease activities. Crystal structures of human and bacterial FAN1 bound to a DNA flap have been solved. The Pseudomonas aeruginosa bacterial FAN1 and human FAN1 (hFAN1) missing a...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier B.V.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7105229/ https://ncbi.nlm.nih.gov/pubmed/29518739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.02.007 |
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