Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription

Coronaviruses contain a positive-sense single-stranded genomic (g) RNA, which encodes nonstructural proteins. Several subgenomic mRNAs (sgmRNAs) encoding structural proteins are generated by template switching from the body transcription regulatory sequence (TRS) to the leader TRS. The process prefe...

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Vydáno v:Cell Host Microbe
Hlavní autoři: Wu, Chia-Hsin, Chen, Pei-Jer, Yeh, Shiou-Hwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104987/
https://ncbi.nlm.nih.gov/pubmed/25299332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.09.009
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